The Significance of Citrate Plasma in Clinical Chemistry and Immunochemistry Tests
Summary
- Citrate plasma is suitable for specific clinical chemistry and immunochemistry tests in exceptional circumstances
- It is commonly used in coagulation studies and for certain immunoassays
- Proper collection, handling, and processing of citrate plasma samples are essential for accurate Test Results
Introduction
In a medical lab setting, various types of specimens are collected and tested to aid in the diagnosis and treatment of patients. One type of specimen that is commonly used for certain clinical chemistry and immunochemistry tests is citrate plasma. Citrate plasma is a type of blood specimen that is collected using citrate as an anticoagulant. In certain exceptional circumstances, citrate plasma may be the preferred specimen for specific tests due to its unique properties and characteristics.
Coagulation Studies
Citrate plasma is commonly used in coagulation studies to assess a patient's ability to form blood clots. Coagulation tests, such as Prothrombin Time (PT) and Activated Partial Thromboplastin Time (aPTT), require citrate plasma as the Anticoagulant of choice. Citrate works by binding to calcium ions, which are required for the coagulation cascade, thereby preventing blood from clotting within the tube.
Immunoassays
In addition to coagulation studies, citrate plasma is suitable for certain immunoassays that require a plasma specimen. Immunoassays are tests that detect the presence of specific proteins or antibodies in the blood. Citrate plasma can be used for immunoassays such as enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay (RIA) when serum is not available or when plasma is specifically requested by the ordering physician.
Quality Control and Data Management
Proper collection, handling, and processing of citrate plasma samples are essential for ensuring the accuracy and reliability of Test Results. Quality Control measures, such as verifying the patient's identity, labeling the specimen correctly, and maintaining proper storage conditions, must be followed to prevent preanalytical errors. In addition, proper data management practices, such as documenting the date and time of collection, are necessary for tracking and tracing specimens throughout the testing process.
Conclusion
Citrate plasma is a valuable specimen for specific clinical chemistry and immunochemistry tests in certain exceptional circumstances in a medical lab setting in the United States. It is commonly used in coagulation studies and for certain immunoassays that require a plasma specimen. Proper collection, handling, and processing of citrate plasma samples are essential for ensuring the accuracy and reliability of Test Results.
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