Clinical Chemistry and Immunochemistry Tests Requiring Citrate Plasma in a Medical Laboratory Setting

Summary

• Citrate plasma is commonly used in medical laboratories for various clinical chemistry and immunochemistry tests.
• Tests that require the use of citrate plasma include coagulation assays, liver function tests, and specific immunochemistry assays.
• The proper collection and handling of citrate plasma samples are crucial to ensure accurate Test Results in a medical laboratory setting.

Clinical Chemistry and Immunochemistry Tests Requiring Citrate Plasma in a Medical Laboratory Setting

Introduction

In a medical laboratory setting, various clinical chemistry and immunochemistry tests are conducted to diagnose diseases, monitor treatment effectiveness, and assess overall patient health. One common type of specimen used for these tests is citrate plasma, which is crucial for specific assays. This article aims to explore the specific clinical chemistry and immunochemistry tests that require the use of citrate plasma in the United States.

Coagulation Assays

Citrate plasma is commonly used for coagulation assays to evaluate how well blood clots. The most widely performed coagulation test using citrate plasma is the Prothrombin Time (PT) test, which measures how long it takes for blood to clot. Other coagulation assays that require citrate plasma include:

1. Activated Partial Thromboplastin Time (aPTT) test
2. Thrombin Time test
3. D-Dimer test

Liver Function Tests

Liver function tests are essential for evaluating the overall health and function of the liver. Citrate plasma is used in specific liver function tests to measure the levels of various enzymes and proteins in the blood. Some common liver function tests that require citrate plasma include:

1. Alanine aminotransferase (ALT) test
2. Aspartate aminotransferase (AST) test
3. Alkaline phosphatase (ALP) test
4. Bilirubin test

Specific Immunochemistry Assays

In addition to coagulation assays and liver function tests, citrate plasma is also used in specific immunochemistry assays to measure the presence of various antibodies or antigens in the blood. Some immunochemistry tests that require citrate plasma include:

1. Antiphospholipid antibody test
2. Factor V Leiden mutation test
3. von Willebrand factor antigen test
4. ADAMTS13 activity assay

Collection and Handling of Citrate Plasma Samples

Proper collection and handling of citrate plasma samples are crucial to ensure accurate Test Results in a medical laboratory setting. The following steps should be followed when collecting and handling citrate plasma samples:

1. Use a syringe or vacutainer tube containing citrate as the anticoagulant.
2. Fill the tube with the appropriate amount of blood, ensuring proper mixing of the citrate with the blood sample.
3. Centrifuge the tube to separate the plasma from the cellular components of the blood.
4. Transfer the citrate plasma to a labeled storage container and store it at the recommended temperature until testing.

Conclusion

Citrate plasma plays a crucial role in various clinical chemistry and immunochemistry tests conducted in medical laboratory settings in the United States. Tests such as coagulation assays, liver function tests, and specific immunochemistry assays require the use of citrate plasma to ensure accurate and reliable results. Proper collection and handling of citrate plasma samples are essential to maintain the integrity of the specimens and obtain precise Test Results. By understanding the specific tests that require the use of citrate plasma and following best practices for sample collection and handling, medical laboratory professionals can ensure the quality of diagnostic testing for their patients.

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